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See HFC39 Products

HFC39 Series couplings provide aseptic disconnect functionality. Automatic shutoff valves close off the flow path at disconnection, protecting valuable media while also eliminating the need for pinch clamps and tube welders. An easy-to-use thumb latch design provides a secure, leak-free connection as well as enabling one-handed disconnects.

Assets & Downloads

Features Benefits
Automatic shutoff valves Validated aseptic disconnect for pre-sterilized systems
Audible “click” Provides confidence of a secure
Lightweight Easy integration with single-use tube assemblies
BSE/TSE free materials Meet ADCF requirements

Specifications & CV Value

Operating Conditions (Fluid Transfer)

Pressure: Vacuum to 125 psi, 8.62 bar
Temperature: -40°F (-40°C) to 280°F (138°C)


Main components: Polysulfone (amber tint), USP Class VI, ADCF
O-rings: Silicone (clear), platinum-cured, USP Class VI, ADCF
Springs: 316 stainless steel


Gamma: Up to 50 kGy gamma irradiation. Sterilize coupled or uncoupled.
Autoclave: Up to 270°F (132°C) for 60 minutes. Up to 25 repetitions for uncoupled units and one cycle for coupled units.

Cv Value

Cv ~ 1.6 (23.05) max
Cv ~ 1.5 (21.61) max
Cv values are based on gpm and psi, and Ipm and bar (shown in parentheses).
WARNING: Pressure, temperature, chemicals and operating environment can affect the performance of couplings. It is the customer’s responsibility to test the suitability of Colder products in their own application conditions.

Validation Reports

Extractables Reports





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Caps & Plugs

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