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    See HFC39 Products

    HFC39 Series couplings provide aseptic disconnect functionality. Automatic shutoff valves close off the flow path at disconnection, protecting valuable media while also eliminating the need for pinch clamps and tube welders. An easy-to-use thumb latch design provides a secure, leak-free connection as well as enabling one-handed disconnects.

    Assets & Downloads

    Features Benefits
    Automatic shutoff valves Validated aseptic disconnect for pre-sterilized systems
    Audible “click” Provides confidence of a secure
    Lightweight Easy integration with single-use tube assemblies
    BSE/TSE free materials Meet ADCF requirements

    Specifications & CV Value

    Operating Conditions (Fluid Transfer)

    Pressure: Vacuum to 125 psi, 8.62 bar
    Temperature: -40°F (-40°C) to 280°F (138°C)


    Main components: Polysulfone (amber tint), USP Class VI, ADCF
    O-rings: Silicone (clear), platinum-cured, USP Class VI, ADCF
    Springs: 316 stainless steel


    Gamma: Up to 50 kGy gamma irradiation. Sterilize coupled or uncoupled.
    Autoclave: Up to 270°F (132°C) for 60 minutes. Up to 25 repetitions for uncoupled units and one cycle for coupled units.

    Cv Value

    Cv ~ 1.6 (23.05) max
    Cv ~ 1.5 (21.61) max
    Cv values are based on gpm and psi, and Ipm and bar (shown in parentheses).
    WARNING: Pressure, temperature, chemicals and operating environment can affect the performance of couplings. It is the customer’s responsibility to test the suitability of Colder products in their own application conditions.

    Validation Reports

    Extractables Reports





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